Blood Coagulation DEMO

Introduction
Introduction Platelets Haemostatic Plug Formation Coagulation Thrombolytic Mechanisms
Introduction Bleeding Time Coagulation Tests
Introduction Case 1 Case 2 Case 3 Case 4 Case 5
Start Questions
Glossary

Case 1 - History

A 35 year old man presented to his doctor with the following symptoms: melaena, tendency to bruising, and weight loss over the last few weeks.

On examination he showed multiple petechiae and purpura on limbs, and an enlarged spleen.

Glossary

Melaena - This is a condition of the stools in which dark, tarry masses are passed from the bowel. It is due to bleeding from the stomach or from the higher part of the bowel, the blood undergoing chemical changes under the action of gastric secretions, and being finally converted in large part into sulphide of iron.

Bruising (extravasations) - An escape of fluid from the vessels which ought to contain it ('a bruise').